GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs1056667 | 1 | rs6924838 | chr6:26571756 | LOC100270746 | chr6:26987146-26988085:- | -0.14 | -3.36 | 0.000857 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6924838 | chr6:26571756 | ZNF322A | chr6:26634612-26659963:- | -0.16 | -4.59 | 5.75E-6 | Educational attainment |
| THCA | cis | rs751728 | 1 | rs6925273 | chr6:33732448 | LEMD2 | chr6:33738991-33756906:- | -0.3 | -6.72 | 5.1E-11 | Crohn's disease |
| THCA | cis | rs1056667 | 1 | rs6925703 | chr6:26521589 | BTN2A3 | chr6:26422317-26431927:+ | 0.19 | 4.52 | 7.82E-6 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6925703 | chr6:26521589 | HCG11 | chr6:26521934-26527610:+ | -0.23 | -4.43 | 1.19E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6925703 | chr6:26521589 | HMGN4 | chr6:26538572-26547162:+ | -0.16 | -4.05 | 5.86E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6925703 | chr6:26521589 | ZNF322A | chr6:26634612-26659963:- | -0.14 | -3.77 | 0.00018 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6925895 | chr6:26572165 | BTN2A3 | chr6:26422317-26431927:+ | 0.18 | 4.22 | 2.98E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6925895 | chr6:26572165 | HCG11 | chr6:26521934-26527610:+ | -0.21 | -4.11 | 4.7E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6925895 | chr6:26572165 | HMGN4 | chr6:26538572-26547162:+ | -0.16 | -4.16 | 3.71E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6925895 | chr6:26572165 | LOC100270746 | chr6:26987146-26988085:- | -0.14 | -3.36 | 0.000857 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6925895 | chr6:26572165 | ZNF322A | chr6:26634612-26659963:- | -0.16 | -4.59 | 5.75E-6 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6926629 | chr6:26499903 | BTN2A3 | chr6:26422317-26431927:+ | 0.19 | 4.54 | 7.18E-6 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6926629 | chr6:26499903 | HCG11 | chr6:26521934-26527610:+ | -0.23 | -4.54 | 7.04E-6 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6926629 | chr6:26499903 | HMGN4 | chr6:26538572-26547162:+ | -0.16 | -4 | 7.43E-5 | Educational attainment |